Melanotan 2 (10mg)
Melanotan 2 (10mg) — Clinical Overview, Mechanism of Action & Provider Dosing Guide
Overview: What Is Melanotan 2 (10mg)?
Melanotan 2 (10mg) is a melanocortin peptide used to increase natural melanin production, support UV protection, and enhance sexual arousal pathways. It allows patients to achieve visibly darker skin with less direct sun exposure while also delivering benefits in libido and mood.
Key Benefits of Melanotan 2 (10mg)
- Enhances Natural Tanning Response
- Reduces UV-Related Skin Damage Risk
- Improves Skin Tone Uniformity
- Boosts Libido and Sexual Arousal
- May Support Confidence in Aesthetic Goals
- Useful for Fair or Photosensitive Skin Types
- Assists in Long-Term Pigment Retention
Mechanism of Action: How Melanotan 2 (10mg) Works
Melanotan 2 operates via melanocortin receptor pathways:
- MC1 Activation: Increases eumelanin — darker, protective pigmentation
- MC4 Signaling: Enhances libido and arousal sensitivity
- UV Defense: Boosts photoprotection before and after sun exposure
- Pigment Longevity: Stabilizes melanin within skin cells
This enables visible tanning with reduced UV exposure requirements.
Clinical Dosing Guide for Providers
For licensed medical professionals only.
Suggested Dosage
- Loading Phase: 250–500mcg daily (1–2 weeks)
- Maintenance Phase: 500–1000mcg weekly
- Adjust as needed to minimize nausea during titration
Administration Notes
- Route: Subcutaneous injection
- UV activation (short exposure) recommended for color development
- Avoid aggressive early sunlight during adaptation
Common Clinical Stacks
- GHK-Cu — improves skin regeneration
- TA1 — immune resilience and skin-barrier support
Reconstitution & Storage
- Use bacteriostatic water
- Refrigerate after mixing
- ~30-day stability refrigerated
Ideal Candidate Profile
Potentially Good Candidates
- Light-skinned or burn-prone individuals
- Adults seeking a deeper, longer-lasting tan
- Patients wanting libido enhancement as a secondary benefit
- Aesthetic-focused wellness clients
Use With Caution
- History of melanoma or suspicious skin lesions
- Dermatology involvement recommended for high-risk patients
Potential Side Effects
Most effects are mild and temporary:
- Nausea (most common at higher titrations)
- Headache or facial flushing
- Darkening of pre-existing moles or freckles
- Rare appetite increases
Dose escalation speed determines tolerance success.
Frequently Asked Questions (Top 10)
1. What does Melanotan 2 help with?
Skin pigmentation, UV protection, and libido enhancement.
2. How soon will patients notice results?
Often within the first 1–2 weeks during loading.
3. Can it replace sunscreen?
No — still recommended for UV exposure.
4. Does it work without sun?
Yes — but UV exposure improves results significantly.
5. Does it affect mood or confidence?
Often positively due to aesthetic improvements.
6. Does it increase sexual desire?
Common — MC4 receptor activation influences libido.
7. How long does the tan last?
Weeks to months with maintenance dosing.
8. Who should not use it?
Those with active or high-risk skin cancer.
9. Is daily dosing required forever?
Daily only during loading; weekly for maintenance.
10. How is it stored?
Refrigerated once reconstituted.
Melanotan 2 vs Similar Peptides
- vs Melanotan 1:
MT-2 has stronger libido effects and pigmentation intensity. - vs UV Tanning:
Requires less UV exposure for the same color depth. - vs Topical Bronzers:
Internal pigment activation = more natural-appearing tan.
Research & Evidence Overview
Data supports benefits in:
- Eumelanin production + enhanced UV protection
- Sexual-health pathways via MC4 activity
- Improved skin-tone evenness and pigment stability
Widely used in aesthetic medicine due to dual-benefit effects.
Product & Purity Assurance
99% purity pharmaceutical grade
- COA + endotoxin screened
- cGMP manufacturing
- Providers-only availability
Legal & Medical Disclaimer
For licensed medical professionals only. Not intended to diagnose, treat, or cure any condition.

Made in the USA

Third-Party Tested

