LL37 (5mg)
LL-37 (5mg) — Clinical Overview, Mechanism of Action & Provider Dosing Guide
Overview: What Is LL-37 (5mg)?
LL-37 (5mg) is a broad-spectrum antimicrobial and tissue-repair peptide naturally derived from the body’s innate immune system. It has been applied clinically to help combat bacterial, viral, and fungal threats, reduce biofilm formation, and support wound healing and inflammatory control. Due to its versatility, LL-37 is frequently used in immune, dermatological, and regenerative medicine settings.
Key Benefits of LL-37 (5mg)
- Broad-Spectrum Antimicrobial Protection
- Supports Skin & Wound Healing Response
- Helps Reduce Biofilm & Chronic Infection Risk
- Anti-Inflammatory and Immune-Modulating Effects
- May Support Gut and Mucosal Barrier Health
- Promotes Tissue Regeneration & Recovery
- Useful in Recurrent or Treatment-Resistant Infections
Mechanism of Action: How LL-37 (5mg) Works
LL-37 supports both innate immune defense and tissue recovery:
- Membrane Disruption of Pathogens: Destroys harmful microbes directly
- Immune Activation Modulation: Enhances immune coordination without overactivation
- Biofilm Breakdown: Helps disrupt microbial defense layers
- Angiogenesis & Tissue Repair: Promotes improved healing environments
- Barrier Integrity Support: Strengthens epithelial and mucosal protection
This makes LL-37 valuable for complex immune and recovery scenarios.
Clinical Dosing Guide for Providers
For licensed medical professionals only.
Suggested Dosage
- Typical Range: 100–500mcg 2–3x weekly
- Duration: 4–8+ weeks depending on therapeutic goals
Administration Notes
- Route: Subcutaneous injection or provider-directed targeted administration
- Common Clinical Stacks:
- BPC-157 — synergistic wound and GI repair
- TA1 — immune-strength enhancement
- TB-500 — connective tissue recovery
Reconstitution & Storage
- Reconstitute with bacteriostatic water
- Refrigerate after mixing
- Stability ~30 days refrigerated
Ideal Candidate Profile
Potentially Good Candidates
- Individuals with recurrent or chronic infection patterns
- Patients needing accelerated wound healing
- Those with compromised skin barrier or ulceration
- Gut barrier dysfunction cases
Use With Caution
- Autoimmune conditions — immune monitoring recommended
- Hyperinflammatory disorders — dose titration required
Potential Side Effects
Generally mild:
- Injection-site redness or warmth
- Temporary fatigue
- Mild inflammatory flare during microbial die-off
Clinical supervision is required due to immune-modulating activity.
Frequently Asked Questions
1. What is LL-37 used for?
Immune defense support and advanced tissue healing.
2. Is it an antibiotic?
No — it is a
natural antimicrobial peptide, not a drug-class antibiotic.
3. Does it help with skin healing?
Yes — frequently used for wounds, ulcers, and dermatologic recovery.
4. Can it fight viral or fungal infections?
Yes — broad-spectrum antimicrobial activity.
5. How quickly does it work?
Healing and immune improvement may appear within 2–4 weeks.
6. Does it help gut health?
It may support mucosal immunity and barrier function.
7. Is it safe long term?
Typically — with appropriate provider oversight.
8. Can it be combined with TA1 or BPC-157?
Common — synergistic immune + repair benefits.
9. Will LL-37 overstimulate immunity?
Generally no — proper dosing helps maintain balance.
10. How is it stored?
Refrigerated post-reconstitution.
LL-37 vs Similar Peptides
- Vs BPC-157:
LL-37 is antimicrobial + immune-driven; BPC focuses on repair. - Vs TA1:
TA1 strengthens immune function; LL-37 actively combats pathogens. - Vs TB-500:
TB-500 supports structural healing; LL-37 adds infection control.
Research & Evidence Overview
Studies support its role in:
- Antimicrobial defense
- Chronic and acute wound recovery
- Biofilm disruption
- Immune-response coordination
- Mucosal protection
A growing therapeutic option in immune and regenerative medicine.
Product & Purity Assurance
99% purity
- COA + endotoxin tested
- cGMP pharmaceutical standards
- Provider-exclusive dispensing
Legal & Medical Disclaimer
For licensed medical professionals only. Not intended to diagnose, treat, or cure any condition.

Made in the USA

Third-Party Tested

