LYSINE-PROLINE-VALINE (10mg)
Lysine-Proline-Valine (10mg) — Clinical Overview, Mechanism of Action & Provider Dosing Guide
Overview: What Is Lysine-Proline-Valine (10mg)?
Lysine-Proline-Valine (10mg), commonly abbreviated KPV, is a potent anti-inflammatory tripeptide derived from the α-MSH hormone sequence. It is widely used to reduce systemic and localized inflammation, support gut barrier health, improve skin healing, and help regulate immune-driven conditions — without immunosuppression.
Key Benefits of Lysine-Proline-Valine (10mg)
- Powerful Systemic and Local Anti-Inflammatory Effect
- Supports Gut Lining Repair & Barrier Protection
- Improves Skin Healing + Reduces Irritation
- Helps Regulate Immune Overactivity
- Reduces Pain Linked to Inflammation
- Potential Relief in IBD, Dermatitis & Joint Conditions
- No Hormonal or Immunosuppressive Downsides
Mechanism of Action: How KPV (10mg) Works
KPV modulates inflammation by acting on α-MSH receptor signaling:
- Cytokine Suppression (TNF-α, IL-6): Reduced inflammatory response
- Barrier Repair Activation: Supports epithelial cell healing
- Immune Modulation: Less autoimmune-style overreaction
- Direct Anti-Microbial Support: Protective effect in gut + skin
- Neuroimmune Balance: Reduces stress-mediated flare activity
Net result: less inflammation + faster recovery.
Clinical Dosing Guide for Providers
For licensed medical professionals only.
Suggested Dosage
- Range: 100–300mcg daily
- Cycle Duration: 4–12+ weeks depending on condition
Administration Notes
- Route: Subcutaneous or intranasal based on target tissue
- Common Clinical Stacks:
- BPC-157 — gut & tissue-repair synergy
- TA1 — immune stability enhancement
- GHK-Cu — skin regeneration pairing
Reconstitution & Storage
- Reconstitute with bacteriostatic water
- Refrigerate after mixing
- Stable ~30 days refrigerated
Ideal Candidate Profile
Potentially Good Candidates
- Individuals with chronic or acute inflammation
- Patients with IBD, colitis, leaky gut, or GI irritation
- Skin-injury or dermatitis recovery
- Joint or tendon inflammation cases without high-risk meds
Use With Caution
- Severe autoimmune flare cases — medical monitoring required
- Complex gut illnesses — specialist involvement recommended
Potential Side Effects
Extremely low incidence:
- Mild injection discomfort
- Rare temporary GI changes
- Rare nasal dryness (intranasal route)
Safe for long-term anti-inflammatory support in most patients.
Frequently Asked Questions
1. What does KPV help with?
Inflammation reduction, gut healing, and immune modulation.
2. Does it help with IBS or IBD?
Frequently — supports epithelial healing and reduces inflammatory triggers.
3. Will it affect my immune system negatively?
No — modulates without suppression.
4. Can it help skin issues?
Yes — enhances healing and reduces irritation.
5. Does it work quickly?
Some symptom relief may occur within days to weeks.
6. Is daily dosing required?
Yes — consistent dosing supports continuous inflammation control.
7. Can children use it?
Provider discretion required for pediatric cases.
8. Does it replace steroids?
No — alternative that avoids immunosuppressive side effects.
9. Who should avoid it?
Unmanaged autoimmune disorders without supervision.
10. How is it stored?
Refrigerated after reconstitution.
KPV vs Similar Therapies
- vs BPC-157:
KPV focuses on inflammation, BPC on repair — strong synergy when combined. - vs GHK-Cu:
KPV is systemic inflammation control vs. skin/collagen emphasis. - vs NSAIDs / Steroids:
No GI, cardiac, or suppression-related drawbacks.
Research & Evidence Overview
Supported benefits include:
- Major reductions in inflammatory cytokines
- Significant improvements in gut barrier protection
- Symptom relief in IBD & inflammatory skin disorders
- Excellent safety profile
A well-validated peptide in inflammation management care.
Product & Purity Assurance
99% purity
- COA + endotoxin certified
- cGMP manufacturing
- Provider-restricted access
Legal & Medical Disclaimer
For licensed medical professionals only. Not intended to diagnose, treat, or cure any condition.

Made in the USA

Third-Party Tested

