Thymosin Beta 4 (TB500) (5mg)
Thymosin Beta 4 (TB-500) (5mg) — Clinical Overview, Mechanism of Action & Provider Dosing Guide
Overview: What Is Thymosin Beta 4 (TB-500) (5mg)?
Thymosin Beta 4 (TB-500) (5mg) is a tissue-regenerative peptide designed to accelerate recovery from musculoskeletal injury, improve cellular repair, and support performance-driven rehabilitation. TB-500 is a synthetic version of a naturally occurring protein involved in wound healing, angiogenesis, and cellular restructuring — making it valuable in both acute injury and long-term structural resilience.
Key Benefits of TB-500 (5mg)
- Accelerated Muscle & Fascia Repair – beneficial after injuries or intense training.
- Enhanced Tendon & Ligament Recovery – supports structural tissue integrity.
- Improved Joint Mobility – reduces stiffness and enhances movement patterns.
- Boosted Angiogenesis – increases blood flow to damaged areas for faster healing.
- Reduced Inflammation & Pain – modulates cellular stress responses.
- Supports Nerve Healing – potential neuroprotective activity.
- Well-Tolerated Regenerative Therapy – suitable for longer recovery cycles.
Mechanism of Action: How TB-500 (5mg) Works
TB-500 promotes regeneration through multiple cellular pathways:
- Actin Modulation: Enhances cell mobility and structural repair processes.
- Growth-Factor Enhancement: Speeds tissue regeneration and remodeling.
- Angiogenesis Support: Promotes new blood vessel formation for nutrient delivery.
- Reduced Adhesion Formation: Supports healthy healing post-injury or surgery.
- Anti-Inflammatory Effects: Decreases excessive inflammatory cascade activity.
This 5mg dosage is commonly used as a starting point in muscle, tendon, ligament, and fascia recovery cases.
Clinical Dosing Guide for Providers
For licensed medical professionals only.
Suggested Dosage
- Standard Range: 2–5mg weekly
- Administration Timing: 1–2 injections per week toward injury recovery goals
- Cycle Duration: 4–8+ weeks depending on condition severity
Administration Notes
- Route: Subcutaneous injection, preferably near injury when clinically appropriate
- Common Clinical Stacks:
- BPC-157 — soft-tissue + gut repair synergy
- GH Secretagogues — improved recovery environment
- Anti-inflammatory stacks — for complex injury cases
Reconstitution & Storage
- Reconstitute with bacteriostatic water
- Refrigerate after reconstitution
- Approx. 30-day shelf life
Ideal Candidate Profile
Potentially Good Candidates
- Athletes and active individuals under heavy physical load
- Patients healing from orthopedic injuries or surgeries
- Those experiencing chronic tendon or ligament strain
- Individuals with reduced mobility due to tissue degeneration
Use With Caution
- Patients with systemic autoimmune disorders — oversight required
- Those with uncontrolled chronic illness until medically stabilized
Potential Side Effects
Generally mild and temporary:
- Injection-site irritation
- Mild headache or fatigue
- Rare GI sensitivity changes
TB-500 has a strong safety profile due to its non-hormonal regenerative nature.
Frequently Asked Questions
1. What does TB-500 (5mg) help with?
Soft-tissue repair, mobility improvement, and recovery support.
2. How quickly does it work?
Many patients experience improvement within 1–3 weeks.
3. Is TB-500 safe long-term?
Typically yes — when monitored by a licensed provider.
4. Can it be used after surgery?
Yes — commonly integrated into post-surgical rehabilitation plans.
5. Does it help tendons and ligaments?
Yes — supports structural tissue regeneration and function.
6. Does it reduce inflammation?
It helps regulate inflammation while promoting real tissue repair.
7. How often is it injected?
1–2 times weekly depending on injury demands.
8. Can TB-500 be combined with BPC-157?
Yes — one of the most widely used regenerative peptide stacks.
9. How long do patients stay on TB-500?
Typically 4–8+ weeks depending on healing progress.
10. How is it stored?
Refrigerate after mixing and maintain sterile technique.
TB-500 (5mg) vs Similar Peptides
- TB-500 vs BPC-157:
TB-500 excels in muscle & fascia repair; BPC-157 leads in tendon & gut healing. - TB-500 vs GH Peptides:
GH peptides enhance healing conditions — TB-500 directly promotes repair. - TB-500 vs NSAIDs:
NSAIDs mask symptoms; TB-500 supports structural recovery.
Research & Evidence Overview
Studies suggest TB-500 may support:
- Muscle + connective tissue regeneration
- Enhanced healing post-surgery
- Improved angiogenesis and blood flow
- Functional mobility recovery
- Reduced inflammatory signaling
Clinical use continues to expand in sports medicine and rehabilitation.
Product & Purity Assurance
99% purity
- COA & endotoxin verified
- cGMP pharmaceutical production
- Licensed provider dispensing only
Legal & Medical Disclaimer
This content is intended only for licensed medical professionals. This peptide is not intended to diagnose, treat, or cure any condition.

Made in the USA

Third-Party Tested

