MOTS-c (40mg)
MOTS-c (40mg) — Clinical Overview, Mechanism of Action & Provider Dosing Guide
Overview: What Is MOTS-c (40mg)?
MOTS-c (40mg) is a mitochondria-derived metabolic peptide designed to improve energy production, insulin sensitivity, cellular resilience, and exercise performance. It enhances metabolic efficiency at the cellular level — supporting both fat loss and endurance improvements.
Key Benefits of MOTS-c (40mg)
- Enhances Mitochondrial Energy Output (ATP)
- Improves Insulin Sensitivity & Glucose Usage
- Supports Fat Loss & Body-Composition Health
- Boosts Endurance + Exercise Adaptation
- Promotes Cellular Stress Resistance
- Improves Recovery & Vitality
- Synergistic With Weight-Loss Peptides
Mechanism of Action: How MOTS-c (40mg) Works
MOTS-c regulates AMPK and mitochondrial metabolic pathways:
- AMPK Activation: Increases fat metabolism and glucose uptake
- Improved Mitochondrial Biogenesis: Strengthens cell energy systems
- Stress Resilience Enhancement: Better adaptation to physical + metabolic load
- Muscle-Endurance Benefits: Increased stamina and training output
- Glucose Regulation: Better insulin signaling for metabolic efficiency
Net effect: more energy, better fat burn, and improved cellular longevity.
Clinical Dosing Guide for Providers
For licensed medical professionals only.
Suggested Dosage
- Typical Range: 10–15mg 2–3x per week
- Cycle Duration: 4–12 weeks depending on goals
Administration Notes
- Route: Subcutaneous injection
- Best Timing: Pre-training or daytime for energy utilization
Common Clinical Stacks
- GLP-1 analogs — dual appetite + metabolic support
- 5-Amino-1MQ — enhanced fat-burning synergy
- Epithalon — longevity + mitochondrial pairing
Reconstitution & Storage
- Reconstitute using bacteriostatic water
- Keep refrigerated after mixing
- ~30-day stability when stored properly
Ideal Candidate Profile
Potentially Good Candidates
- Athletes seeking stronger endurance or conditioning
- Overweight adults with low energy and metabolic slowdown
- Patients with insulin resistance or glucose imbalance
- Individuals focused on cellular aging and performance enhancement
Use With Caution
- Diabetics — require glucose monitoring
- Thyroid/metabolic disorders — physician oversight recommended
Potential Side Effects
Typically mild and self-limiting:
- Temporary injection-site irritation
- Light headache during dose changes
- Rare fatigue during mitochondrial adaptation
Excellent tolerability shown in clinical use.
Frequently Asked Questions
1. What does MOTS-c help with?
Metabolism, energy, exercise capacity, and fat loss.
2. How quickly does it work?
Many experience improved energy within 1–2 weeks.
3. Is this a weight-loss drug?
Not directly — it improves
metabolic efficiency, which enhances results.
4. Can it be used for athletics?
Yes — supports endurance and recovery.
5. Does it help with aging?
Better mitochondrial output contributes to
healthy aging.
6. Does it affect appetite?
No — best paired with GLP-1 peptides for hunger control if needed.
7. Is cycling required?
Common — for mitochondrial responsiveness.
8. Can MOTS-c stack with NAD+?
Very well — strong cellular longevity synergy.
9. Is it safe long-term?
Cycles recommended with medical monitoring.
10. How is it stored?
Refrigerated after reconstitution.
MOTS-c vs Similar Peptides
- vs 5-Amino-1MQ:
1MQ increases metabolic burn; MOTS-c energizes cells. - vs GLP-1 therapies:
GLP-1 reduces appetite; MOTS-c maximizes exercise + metabolism. - vs Epithalon:
MOTS-c targets energy pathways vs. genetic aging pathways.
Research & Evidence Overview
Clinical and preclinical evidence supports:
- Increased mitochondrial biogenesis
- Better glucose tolerance and AMPK activation
- Improved endurance + aerobic performance
- Protective role against age-related metabolic decline
A major tool in metabolic and performance medicine.
Product & Purity Assurance
99% purity
- COA and endotoxin screened
- cGMP pharmaceutical production
- Licensed provider–only peptide
Legal & Medical Disclaimer
For licensed medical professionals only. Not intended to diagnose, treat, or cure any condition.

Made in the USA

Third-Party Tested

