5-amino-1mq (5mg)
5-Amino-1MQ (5mg) — Clinical Overview, Mechanism of Action & Provider Dosing Guide
Overview: What Is 5-Amino-1MQ (5mg)?
5-Amino-1MQ (5mg) is a metabolic enhancement peptide that targets the Nicotinamide N-Methyltransferase (NNMT) pathway to improve fat metabolism, increase energy output, and support healthier body composition. By reducing NNMT activity, 5-Amino-1MQ helps restore metabolic efficiency in patients with obesity, metabolic slowdown, or stubborn fat-loss resistance.
Key Benefits of 5-Amino-1MQ (5mg)
- Improves Metabolic Rate & Cellular Energy Expenditure
- Supports Fat Reduction & Better Body Composition
- Preserves Lean Muscle Mass During Weight Loss
- Enhances Exercise Output & Overall Vitality
- Reduces Adipocyte (Fat Cell) Size & Accumulation
- Supports Glucose Control & Insulin Sensitivity
- Useful in Weight-Loss Plateaus or Slow Responders
Mechanism of Action: How 5-Amino-1MQ (5mg) Works
5-Amino-1MQ works by selectively inhibiting NNMT, a metabolic enzyme that contributes to slowed energy expenditure:
- NNMT Inhibition: Restores efficient NAD+ utilization
- Enhanced Fat Mobilization: Encourages stored fat breakdown
- Improved Mitochondrial Metabolism: Boosts cellular fuel production
- Increased Thermogenic Activity: Raises baseline energy output
- Better Muscle + Fat Partitioning: Preserves lean mass while cutting fat
Together, these changes support more efficient calorie burn and improved metabolic function.
Clinical Dosing Guide for Providers
For licensed medical professionals only.
Suggested Dosage
- Standard Range: 50–100mg weekly equivalent (divided into daily microdoses)
- Cycle Duration: 4–12+ weeks based on metabolic goals
Note: Contains 5mg per vial — multi-vial regimens are commonly used.
Administration Notes
- Route: Subcutaneous injection
- Common Clinical Stacks:
- GLP-1 analogs — appetite + glucose synergy
- MOTS-c — mitochondrial and exercise support
- AOD-9604 — amplified fat-loss response
Reconstitution & Storage
- Mix with bacteriostatic water per clinic protocol
- Refrigerate after reconstitution
- ~28–30 day stability refrigerated
Ideal Candidate Profile
Potentially Good Candidates
- Patients with slow metabolism or fat-loss resistance
- Individuals with weight regain or plateaus on standard treatments
- Those with insulin control concerns or metabolic syndrome
- Athletes aiming to preserve muscle while reducing fat
Use With Caution
- Uncontrolled diabetes — monitor blood glucose
- Significant cardiovascular disease — medical review required
Potential Side Effects
Most effects are mild and temporary:
- Increased warmth or thermogenic sensation
- Mild muscle tightness
- Temporary injection-site irritation
- Rare: headache or nausea if aggressive dosing
Typically well tolerated when properly titrated.
Frequently Asked Questions
1. What does 5-Amino-1MQ (5mg) help with?
Improving metabolic efficiency and supporting fat reduction.
2. How fast does it work?
Changes in energy and appetite may appear within 1–3 weeks.
3. Does it build muscle?
It
preserves muscle while promoting fat loss.
4. Can it be stacked with GLP-1 therapies?
Extremely common — metabolic + appetite synergy.
5. Does it help stubborn fat areas?
Yes — improves overall metabolic burn rate.
6. Does it affect appetite directly?
Not strongly — works primarily on metabolism, not hunger.
7. Weekly or daily dosing?
Daily microdosing for consistent NNMT pathway suppression.
8. Who should avoid it?
Patients with high-risk metabolic disease without monitoring.
9. Will weight come back after stopping?
Lifestyle + metabolic improvements influence long-term results.
10. How is it stored?
Refrigerated post-reconstitution.
5-Amino-1MQ vs Similar Options
- vs GLP-1 Analogues:
GLP-1 reduces hunger; 1MQ increases calorie burn — strong stack. - vs AOD-9604:
AOD targets fat-breakdown signaling; 1MQ increases energy utilization. - vs Stimulants:
1MQ improves metabolism without nervous system stimulation.
Research & Evidence Overview
Clinical and mechanistic research supports:
- Enhanced metabolic rate via NNMT inhibition
- Decreased adipocyte mass and fat accumulation
- Better muscle preservation during weight loss
- Improvements in metabolic resistance markers
A rapidly growing tool in modern metabolic medicine.
Product & Purity Assurance
99% purity verified
- COA + endotoxin tested
- cGMP-manufactured
- Provider-exclusive dispensing
Legal & Medical Disclaimer
For licensed medical professionals only. Not intended to diagnose, treat, or cure any condition.

Made in the USA

Third-Party Tested

